Nomura Chemical Co., Ltd. Japan • Akira Analytical Solutions Pvt. Ltd. India
USP HPLC Packings – Develosil Columns
Find Develosil phases under their USP L packing classifications for method transfer, pharmacopeial review, equivalent phase selection and customer documentation.
Nomura Chemical Co., Ltd.
15, Hinode-cho, Seto, Aichi 489-0004, Japan
Tel: +81-561-48-1853
Fax: +81-561-48-1434
Email: info@develosil.net
Akira Analytical Solutions Pvt. Ltd.
MIG-1, Plot No. 02, 9th Phase, KPHB Colony,
Kukatpally, Hyderabad – 500085, Telangana, India
Mobile: +91 93918 52431
Email: sales@akiralabs.com
Website: https://akiralabs.com/
USP Listing for Develosil Phases
Develosil columns manufactured by Nomura Chemical are shown below with the USP L classification available on the Develosil USP reference page. Customers can use this page to identify the relevant phase family before checking the detailed product pages for part number, particle size, internal diameter and length.
For validated methods, the USP packing class is only the starting point. Final selection must also match the method requirement, particle size, column dimensions, mobile phase compatibility, and system suitability criteria.
USP Listing Table
| USP L Packing | Develosil column / phase | Stationary phase type | USP packing definition | Manufacturer |
|---|---|---|---|---|
| L1 | Develosil ODS | C18 / ODS (Reversed-phase) | Octadecyl silane chemically bonded to porous or non-porous silica or ceramic micro-particles, 1.5 to 10 µm in diameter, or a monolithic rod. | Nomura Chemical |
| L10 | Develosil CN-UG | Cyano (CN) (Reversed/Normal-phase) | Nitrile groups chemically bonded to porous silica particles, 1.5 to 10 µm in diameter, or a monolithic silica rod. | Nomura Chemical |
| L13 | Develosil TMS-UG C1 | C1 / Trimethylsilane (Low retention RP) | Trimethylsilane chemically bonded to porous silica particles, 3 to 10 µm in diameter. | Nomura Chemical |
| L62 | Develosil C30 | C30 (shape-selective RP) | C30 silane bonded phase on a fully porous spherical silica, 3 to 15 µm in diameter. | Nomura Chemical |
| L62 | Develosil C30-UG | C30 (UG series) | C30 silane bonded phase on a fully porous spherical silica, 3 to 15 µm in diameter. | Nomura Chemical |
| L62 | Develosil RP-Aqueous | Aqueous-compatible RP | C30 silane bonded phase on a fully porous spherical silica, 3 to 15 µm in diameter. | Nomura Chemical |
| L62 | Develosil Combi-RP | Hybrid selectivity RP | C30 silane bonded phase on a fully porous spherical silica, 3 to 15 µm in diameter. | Nomura Chemical |
| L62 | Develosil RP-Aqueous-AR | Aqueous-compatible RP (AR) | C30 silane bonded phase on a fully porous spherical silica, 3 to 15 µm in diameter. | Nomura Chemical |
Tip: Use this table for regulatory documentation, method transfer and choosing an equivalent Develosil chemistry when a method mentions only the USP L packing.
What the USP Packings Mean for Develosil Selection
USP L1 – Develosil ODS
USP definition: Octadecyl silane chemically bonded to porous or non-porous silica or ceramic micro-particles, 1.5 to 10 µm in diameter, or a monolithic rod.
Develosil ODS is the C18 reversed-phase option for broad HPLC use. It is a preferred starting point for routine assay, impurity profiling, stability studies, QC methods and general pharmaceutical separations where strong hydrophobic retention is required.
USP L10 – Develosil CN-UG
USP definition: Nitrile groups chemically bonded to porous silica particles, 1.5 to 10 µm in diameter, or a monolithic silica rod.
Develosil CN-UG provides cyano selectivity. It can be useful when C18 does not give enough resolution, when a mid-polar surface is preferred, or when the method requires an orthogonal selectivity option for polar, aromatic or isomeric compounds.
USP L13 – Develosil TMS-UG C1
USP definition: Trimethylsilane chemically bonded to porous silica particles, 3 to 10 µm in diameter.
Develosil TMS-UG C1 is a low-retention reversed-phase option. It is useful when C18 retains compounds too strongly, when faster elution is needed, or when a validated method specifically asks for a C1 or trimethylsilane bonded phase.
USP L62 – Develosil C30 Family
USP definition: C30 silane bonded phase on a fully porous spherical silica, 3 to 15 µm in diameter.
Develosil C30, C30-UG, RP-Aqueous, Combi-RP and RP-Aqueous-AR fall under L62 on the Develosil USP reference. C30 chemistry is selected for enhanced shape selectivity and can support separations involving carotenoids, lipids, positional isomers, geometrical isomers and aqueous-compatible reversed-phase requirements.
Frequently Asked Questions
Which USP L packing is Develosil ODS?
Develosil ODS is listed under USP L1. L1 is the octadecyl silane, ODS or C18 reversed-phase category used in many routine HPLC methods.
Which USP L packing is Develosil CN-UG?
Develosil CN-UG is listed under USP L10. L10 is a cyano or nitrile bonded phase that can provide different selectivity from C18.
Which USP L packing is Develosil TMS-UG C1?
Develosil TMS-UG C1 is listed under USP L13. L13 is a trimethylsilane bonded C1 packing used when lower reversed-phase retention is required.
Which Develosil phases are listed under USP L62?
Develosil C30, Develosil C30-UG, Develosil RP-Aqueous, Develosil Combi-RP and Develosil RP-Aqueous-AR are listed under USP L62.
What is the USP L62 definition?
USP L62 refers to a C30 silane bonded phase on fully porous spherical silica, typically used for C30 shape-selective reversed-phase separations.
Can Akira help confirm a matching Develosil phase?
Yes. Customers can share the USP L classification, method, part number, particle size and column dimension through the enquiry form for support.
Does this USP listing replace method validation?
No. The USP listing is a selection guide. The final column must meet the validated method, pharmacopeial requirements and system suitability criteria.